Intercellular Adhesion Molecule-1 K469E and Angiotensinogen T207M Polymorphisms in Coronary Slow Flow

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Intercellular Adhesion Molecule-1 K469E and Angiotensinogen T207M Polymorphisms in Coronary Slow Flow

OBJECTIVE To investigate intercellular adhesion molecule-1 (ICAM1) and angiotensinogen (AGT) gene polymorphisms, as related to atherosclerosis and endothelial dysfunction, in coronary slow flow (CSF). SUBJECTS AND METHODS The participants in this study were 48 patients with CSF and 67 patients with normal coronary flow as controls. The K469E polymorphism of ICAM1 (rs5498) and the T207M polymo...

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Intercellular Adhesion Molecule-1 K469E Polymorphism and Risk of Coronary Artery Disease: A Meta-Analysis

BACKGROUND Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism has been implicated in susceptibility to coronary artery disease (CAD). Several studies investigated the association of this polymorphism with CAD in different populations but the results were contradictory. A meta-analysis was conducted to assess the association between ICAM-1 K469E polymorphism and CAD susceptibility. ...

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intercellular adhesion molecule-1 (icam-1) polymorphisms and cancer risk: a meta-analysis.

intercellular adhesion molecule-1 (icam-1) lys469glu (k469e) polymorphism and gly 241arg (g241r) polymorphism might play important roles in cancer development and progression. however, the results of previous studies are inconsistent. the aim of this study was to evaluate the association between icam-1 k469e and g241r polymorphisms and the risk of cancer by meta-analysis.a comprehensive literat...

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association between two single base polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease

aim : the present study evaluated the association between g241r and k469e polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease in iranian population.   background : inflammatory bowel disease including ulcerative colitis and crohn’s disease, is a chronic idiopathic inflammatory disease of the gastrointestinal tract. there are two single base polymorphisms of in...

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Intercellular adhesion molecule 1 gene polymorphisms in inflammatory bowel disease.

Intercellular adhesion molecule (ICAM)-1 is a single-chain cell surface glycoprotein that plays an important role in the recruitment of leukocytes at sites of inflammation and is up-regulated in intestinal mucosa of inflammatory bowel disease (IBD). ICAM-1 gene lies on chromosome 19p13, implicated in determining susceptibility to IBD. The human ICAM-1 gene contains two polymorphic sites in codo...

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ژورنال

عنوان ژورنال: Medical Principles and Practice

سال: 2014

ISSN: 1011-7571,1423-0151

DOI: 10.1159/000363451